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Pfizer-BioNTech Vaccine |  Less effective against the South African variant

Pfizer-BioNTech Vaccine | Less effective against the South African variant

A new Israeli study shows that the variant of South African origin can express the immune system produced by the Pfizer-BioNTech vaccine more than other forms of the virus. With 154 cases, Quebec is the Canadian province with the most cases of the South African alternative.




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In clinical trials, the Pfizer-BioNTech mRNA vaccine was found to be 95% effective in preventing symptomatic disease. However, concerns have emerged about the effectiveness of vaccines against the various variants of COVID-19.

A team from Tel Aviv University and the healthcare organization Clalit sequenced samples from 150 Israelis who had tested positive for COVID-19 after receiving two doses of the vaccine. Among these, the prevalence of the southern African variant was eight times higher than the prevalence of unvaccinated people.

The results show that the South African variant makes it possible to cross the defenses of a vaccinated person better than other forms of the virus.

This study, which has not yet been peer-reviewed, is the first to base data from the real world. In Israel, more than 80% of the population aged 16 years and over received at least one dose of the vaccine, especially the Pfizer-BioNTech dose. However, the researchers cautioned that the study was conducted on a very small sample and that more research is needed to confirm these numbers.

This new data contradicts a previous study by the Pfizer-BioNTech Alliance. 1he is Last April, the coalition claimed that its vaccine maintains a very high efficacy against the South African variant of the Coronavirus, as no cases of COVID-19 were observed in South Africa in people who were vaccinated during the third phase.

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The British alternative poses a problem

The Israeli study also showed weaker protection for the B.1.1,7 variant, of British origin, in the weeks following the first dose of the vaccine.

“Some countries are choosing to increase the gap between the first and second vaccines [Pfizer-BioNTech] The study said, from the recommended three-week period to a longer period, it is important to carefully evaluate whether this delay has an effect on the efficacy of the vaccine against strain B.1.1,7.

The results showed that the prevalence of the British variant was 2.6 times higher in people vaccinated with only one dose compared to unvaccinated people. This indicates reduced efficacy of the vaccine against the variant if the recommended time frame is not met.

Progress variables

Canada has so far identified 24,995 variable cases, including 23,611 British variant and 345 South African variant. Almost half of the cases of the South African variant have been identified in Quebec. Ontario, in second place, ranked 75. British Columbia and Alberta ranked 51 and 26, respectively.

The British alternative continues to spread rapidly across the country. Ontario and Alberta are severely affected, with 9,632 and 8,229 cases. For its part, it lists Quebec 1430.

A sharp increase in hospitalization

The effect of the spread of the most contagious species is being felt in Quebec. The province reported 1,535 new COVID-19 cases and 5 other virus-related deaths on Sunday. Hospitalization is on the rise.

Since the start of this pandemic, 326,383 people in Quebec have been infected with COVID-19. Total of 303,039 recovered. The number of cases jumped by 1,535 on Sunday.

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Of the five reported deaths, two occurred in the past day. One death occurred between April 4 and April 9, and another before April 4, with one death recorded at an unknown date.

The data [de dimanche] Worrying, while 58% of the new cases in Quebec are of people under the age of 40, ”said Health Minister Christian Dube.

So far, 10,742 Quebecers have died from virus-related complications.

There are 25 more hospitalizations than on Saturday. A total of 608 patients were hospitalized. Of those, 139 were in intensive care, more than the day before.

The National Institute of Public Health of Quebec (INSPQ) counts 728 new cases of variant screening in Quebec, for a total of 16,173.

Severely affected areas

Additionally, in the preliminary numbers, Capitale-Nationale and Montreal Island remain the hardest hit. They have 331 and 330 new cases, respectively. Authorities recorded 244 additional cases in Chaudière-Appalaches and 157 in Montérégie.

They also reported 89 cases in Laval, 74 in Laurentians, 72 in Lanoudiere, 59 in Ottawa and 52 in Bas-Saint-Laurent.

In the still orange region, there are 40 new cases in Istry, 32 cases in Maurice – Center de Quebec, and 31 cases in Saguenay – Lac Saint-Jean.

In the yellow zone, it appears that we are seeing a resurgence on the northern shore, with seven cases added to twelve the previous day. Gaspésie – les-de-la-Madeleine reported three new cases and Abitibi-Témiscamingue reported seven.

After reaching a new high of 73,023 doses on Friday, vaccination slowed somewhat on Saturday, as 59,447 doses were administered.

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On Friday, 35,961 screening tests were taken in Quebec.